, 1994). CoVs genomic RNA replication is mediated by RNA-directed RNA polymerase (Pol/RdRp) which is also answerable for transcription of the viral RNA genome. There is experimental proof for SARS-CoV that nsp7 and nsp8 activate and confer processivity to the RNA-synthesizing exercise from the polymerase (partitions et al., 2000). The synthesis of
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